Primary Ventures · Healthcare GI Vertical Software · Illustrative TAM Analysis

Gastroenterology: Illustrative TAM Expansion

36,000 GI providers (19,000 MDs + 17,000 APPs) at $800/provider/month.
From traditional EHR to a full vertical OS with embedded Clinical AI.

TAM Expansion
17.3×
vs. traditional EHR
Total TAM · Vertical OS + Clinical AI
$6,002M
17.3× expansion vs. traditional EHR
Clinical AI TAM
$3,728M
Vertical OS Platform
$2.2B
Adjust Assumptions
EHR Price $800/mo
Monthly cost per provider — varies by practice size
$200/mo$1,500/mo
AI Penetration Rate 35%
Share of clinical spend AI can meaningfully address
10%60%
Billing Capture Rate 15%
Vendor take rate on AI-influenced clinical spend
5%25%
Clinical Delivery Base $71B
GI clinical spend after stripping pharma & procedures
$55B$90B
TAM Comparison
Traditional EHR
$346M
Vertical OS Platform
$2.2B
Vertical OS + Clinical AI
$6,002M
Revenue Stream Breakdown
EHR Subscription
$346M
RCM & Billing
$1.1B
Specialty Pharma
$262M
Prior Authorization
$185M
Clinical Workflow
$381M
Vertical OS Subtotal
$2.2B
Clinical AI — base spend × AI penetration × billing capture rate
$3,728M
Vertical OS layers: EHR Subscription · RCM $1.1B · Specialty Pharma $262M · Prior Auth $185M · Clinical Workflow $381M. 36,000 GI providers (19,000 MDs + 17,000 APPs). EHR price varies by practice size ($200–$1,500/provider/month). Clinical AI = Clinical Delivery Base × AI Penetration Rate × Billing Capture Rate. Sources: NIH/UNC 2021, Doximity/ACGEP 2024, AMA 2024, AANP, Grand View Research, CoverMyMeds. Illustrative purposes only.
Drag the sliders to explore Clinical AI assumptions  ·  primary.vc